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KMID : 0367419750160060058
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Journal of Korean Pediatric Society
1975 Volume.16 No. 6 p.58 ~ p.61
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Clinical Effects of Aminodeoxykanamycin on the infectious Disease of Children
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李槿洙/Lee, Keun Soo
金吉中/尹炳海/Kim, Kil Joong/Yoon Byung Hae
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Abstract
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Aminodexykanamycin (Kanendomycin(^?)) is a new antibiotic obtained from a variant strain of streptomyces Kanamyceticus. It is known potent antibiotics against both gram positive and negative organism. Clinical trials of aminodexykanamycin on the infectious disease of children have been carried out at the Department of Pediatrics, National Medical Center and the results were obtained as follows.
1. The Aminodexykanamycin was administered intramuscularily to 37 cases of infected infant and children, consisting of pneumonia, tonsillitis, pharyngitis, sepsis, phelonephritis, empyema, meningitis, osteomyelitis, burn and skin infection.
2. The dose of aminodexykanamycin used was 10~20mg/kg daily.
3. In the clinical trials, the over-all effevtive rate of aminodexykanamycin was 76%.
4. The aminodexykanamycin was found to be effective to both gram positive and negative organism, especially to staphylococcus aureus and E.coli.
5. No side reaction or toxicity was developed during administration of aminodexykanamycin.
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